Inflammatory Caspases Drive IL-33 Release From Skin in Atopic Dermatitis
New research identifies inflammatory caspases as the enzymes that release IL-33 from skin in atopic dermatitis, implicating them in type 2 inflammation.
Topic
Skin Immunology
Topic
Skin Immunology
Hair Follicle Cells Drive Psoriasis Inflammation, EMJ Reports
EMJ reports hair follicle cells actively drive psoriasis inflammation, reframing the follicular unit as a participant in plaque p…
Microneedle Sampling Tracks Skin Immune-Microbiome Dynamics
A medRxiv preprint claims longitudinal microneedle sampling resolves tissue-restricted immune-microbiome dynamics in skin; no coh…
Dermal Fibroblasts Drive Mast Cell Survival in Mouse Skin, Study Finds
A Journal of Investigative Dermatology study identifies dermal fibroblasts and perivascular cells—not keratinocytes—as the critic…
Two Drug Rashes Map to Two Distinct Immune Programs
Single-cell sequencing of 59,608 skin cells from 18 biopsies shows morbilliform drug eruption and SDRIFE run on distinct cytotoxi…